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- SwiSwi
- SwiSwi
- SwiSWV
- SWVSYL
- SylSym
- SymSyn
- SynSys
- SysSzu
- Szuszy
- Soundz, Manny
- Soup (Norwegian rock band)
- Soup (Scottish band)
- Soup (The Grunge Band, Simon Ward)
- Soup Dragons, The
- Soup Dragons, The feat. Reid, Junior
- Soup Dragons, The featuring Reid, Junior
- soupandreas
- Soupcans
- souphis
- Soupir
- Soupshop
- SoupyMan
- Sour (chill electronic artist?)
- Sour Fiction
- Sour Jazz
- Sour Widows
- Source (Tana Barbier)
- Source (Swedish band, with similar style to In Flames)
- Source of Tide
- Source Vibrations
- Source, The (John Truelove, “You Got the Love” feat. Candi Staton)
- Source, The (Anthony B. Stephens, Arnecia Michelle Harris & John Bellamy)
- Source, The (Norwegian jazz)
- Source, The feat. Staton, Candi
- Source, The featuring Staton, Candi
- Sourface (French-english pop quartet)
- Souris déglinguée, La
- Sourya
- Sous-Sol (Indie Chihuahuan native)
- Sousa, John Philip (conductor and composer)
- Sousa, Tiago
- Soutaer, Wim (Belgian singer)
- Soutaisei Riron
- Souter, Martin (English organist, pianist and harpsichordist)
- Souter, Tessa
- South (UK indie rock/breakbeat/downtempo band)
- South 65
- South Arcade
- South Austin Jug Band
- South Border
- South Central (UK producers/remixers)
- South Central Cartel
- South Circle
- South for Winter
- South North (jazz)
- South of Eden
- South of France (Melodic Noise Pop Duo)
- South of You
- South Park (animated TV show created by Matt Stone and Trey Parker)
- South Penguin (Japanese alternative band)
- South San Gabriel
- South Street Player
- South Strip
- South Summit (Australian band)
- South, Eddie
- South, Joe
- Southall, Read
- Southard, Jonny
- Southbound (Southern Gospel group (Brown/Elbe/Hazelton))
- Southbound Beretta
- Southcott
- Southcourt
- Southeast Desert Metal
- Southeast Engine
- Souther, Hillman, Furay Band, The
- Souther, J.D.
- Souther, J.D. feat. Ronstadt, Linda
- Southerly
- Southern
- Southern All Stars (Japanese rock band)
- Southern Avenue
- Southern Backtones
- Southern Christmas Singers, The
- Southern Cross (Ecuadorian power metal band)
- Southern Culture on the Skids
- Southern Death Cult, The (British gothic post-punk band)
- Southern Empire
- Southern Gentlemen (Metal/hard rock (David Chastain))
- Southern Gothic, The
- Southern Halo
- Southern Lights
- Southern Oracle, The (Hungarian metal band)
- Southern Pacific
- Southern Rail
- Southern Raised
- Southern River Band, The (Perth, Australia rock band)
- Southern Sons (90s Australian rock band)
- Southern Tenant Folk Union
- Southern United States Coptic Diocese (Coptic Orthodox Diocese of the Southern United States)
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