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- SweSwi
- SwiSwi
- SwiSwi
- swiSX
- SXSyl
- SylSym
- SymSyn
- SynSys
- SysSzy
- Szyszy
- Siméon, Chyco (jazz musician)
- Simeone, Harry
- Simeone, Harry, The, Chorale
- Simeone, Shaylee
- Simge (Simge Sağın)
- Simi (Nigerian singer and songwriter Simisola Bolatito Ogunleye)
- Simi (released EPs satin & kitty)
- Simia (rap fr)
- Simia Sapiens
- Simian (UK electronic rock band)
- Simian & Justice
- Simian Ghost
- Simian Mobile Disco
- Simian Mobile Disco feat. Deep Throat Choir
- Simian Mobile Disco feat. Ditto, Beth
- Simian Mobile Disco feat. Keating, Chris
- Simian Mobile Disco feat. Lidell, Jamie
- Simian Mobile Disco feat. Taylor, Alexis
- Simian Mobile Disco feat. Telepathe
- Simian Mobile Disco feat. Young Fathers
- Simians (Band)
- Simien, Terrance
- Similar Kind
- Similar Outskirts
- Similea, Angela
- SIMILIVINLIFE
- Similou, The
- Simins, Russell (US drummer, Jon Spencer Blues Explosion)
- Simion
- Simm, Kevin
- Simmer (UK alternative punk band)
- Simmertones, The (Authentic Jamaican Ska)
- Simmonds & Jones
- Simmonds, Aleyce
- Simmonds, Sean
- Simmonds, Stephen
- Simmonds, Verse
- Simmons, Al (Children's artist)
- Simmons, Art
- Simmons, Ben (Singer/Songwriter)
- Simmons, Carla
- Simmons, Diggy
- Simmons, Gene (KISS bassist and vocalist)
- Simmons, Gene (rockabilly musician, aka Jumpin’ Gene Simmons)
- Simmons, J. K.
- Simmons, Jean
- Simmons, John, and His Orchestra
- Simmons, Patrick
- Simmons, Raye
- Simmons, Russell
- Simmons, Ryan (real name Dieter Günther Bohlen)
- Simmons, Sarah (US singer. Competitor on The Voice)
- Simmons, Sophie (daughter of Gene Simmons of KISS)
- Simmons, Tara
- Simms Twins, The
- Simms, Ginny
- Simms, Juliet
- Simms, Lu Ann (American singer)
- Simms, Scott (vocalist & producer)
- Simms, Sterling
- Simms, Tommy (alternative, southern rock)
- Simms, Zachary
- Simmy (South African)
- SIMO (US rock band)
- Simões, JP
- Simojoki, Pekka
- Simola, Seija
- Simon (UK Artist, Monk & Canatella)
- Simon (Russian power electronics)
- Simon & Garfunkel
- Simon & Garfunkel feat. Everly Brothers, The
- Simon & Garfunkel Revival Band
- Simon & Jan
- Simon & Kitty Po
- Simon and Milo
- Simon Barr Sinister
- Simon Bookish
- Simon Brading
- Simon Dawes
- Simon et les Modanais
- Simon Gardner (Welsh DJ)
- Simon I (pseudonym/alias of Simon Proulx)
- Simon Jela (Pop Singer from Frankfurt)
- Simon Jones (on future city records compilation vol. X)
- Simon Joyner Trio
- Simon Kearney
- Simon Lachman
- Simon London + The Spirits (Western Australian band)
- Simon Safhalter (Safhalter Simon)
- Simon Says (American alternative rock band)
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