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- Sam Ragga Band feat. Delay, Jan
- Sam Shackleton (Scottish folk musician)
- Sam Sillah
- Sam Slatcher
- Sam the Kid
- Sam the Sham
- Sam the Sham & the Pharaohs
- Sam Truth
- Sam Willows, The (Singaporean indie pop band)
- Sam Wise (London rapper and House of Pharoahs member)
- Sam, A.M.
- Sam, Leman
- Sam, Mr. (Sam Paquet, Trance)
- Sam, Mr. feat. Claud9
- Sam, Mr. feat. Claud9
- Sam, Mr. feat. Hawkshaw, Kirsty
- Sam, Mr. vs. T99
- Sam, Şevval
- Sam’s (French rapper)
- Sama Y El Expreso De Oriente
- Samaad
- Samadello, Alessandra (Brazilian Contemporany Christian Singer)
- Samādhi (DJ/Record Producer)
- Samadhi (Italian prog band)
- Samael (Swiss metal band)
- Samaeng, Simon
- Samajona
- Samamidon
- Samaniego, Mauro
- Samann (Italian house producer)
- Samant, Vaishali (Playback singer, lyricist, music composer)
- Samanta
- Samanta & Trim Ademi
- Samantha (Samantha Gilbert Garrido)
- Samantha (Belgian singer Christiane Bervoets)
- Samantha 7
- Samantha Boni (Italian Italo-Dance/Euro-Dance act)
- Samantha de Siena
- Samantha Etlar
- Samantha Fu (Soulwax sideproject)
- Samantha Moore (USA Based)
- Samantha Stone
- Samara (Tunisian rapper)
- Samara Joy feat. Clayton, Gerald
- Samara Joy feat. Grasso, Pasquale
- Samara Joy feat. Paterson, Ben
- Samara Lennoxx
- Samarana (French downtempo artist)
- Samardzic, Zeljko
- Samardžić, Željko
- Samaria (singer/songwriter from Oakland, CA)
- Samaris (Icelandic electronica band)
- Samarita
- Samaroo Jets, The
- Samavayo
- Samavayo feat. Sydorenko, Igor
- Samay, Soluna
- samayuzame (Japanese singer-songwriter)
- Samba (German rock band)
- Samba de La Muerte
- Samba De Raiz (Roots Samba showcases a quartet by adding a Brazilian vocalist. The history, stories, and evolving culture of Brazil have all found a home in Samba)
- Samba Mapangala & Orchestre Virunga
- SambaDá (US afro-brazilian band)
- Sambada (UK acid jazz duo)
- Sambasonics
- Sambassadeur
- Sambasunda
- Sambasunda Quintet
- Sambô (Samba-rock group)
- Sambô feat. Dom M Rap
- Sambô feat. Simoninha, Wilson
- SamBoii (Swedish Rapper)
- Sambol, Ryan
- Sambomaster
- Sambora, Richie
- Sambora, Richie, Tritt, Travis & Woodward, Lucy
- Sambox
- Same as Different
- Same Difference (07-14 UK bubblegum pop duo)
- Same Eyes (Synth duo from Ann Arbor)
- Same Persons, The
- Same Side (Kevin Geyer's (Story So Far & Elder Brother) Solo Project)
- Same Suki
- Same Sun, The
- Same, Same (twins Bob & Clint Moffatt)
- Samedi
- Samedov, Alihan
- Sameer Amir (Singer)
- Samestate
- SameStory (Industrial project from Richmond VA)
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