- Una Mas Trio
- UNA MIA (Alt pop R&B singer songwriter from Toronto)
- Unable to Fully Embrace This Happiness (Emoviolence/Screamo band)
- Unabomb (Artist from Michigan)
- Unabomber (Brazilian punk band)
- Unalei
- UnAlfabet
- Unamerican
- Unamused Dave
- Unanimated
- Unantastbar
- Unashamed
- UNAVERAGE GANG
- UNAVERAGE GANG feat. Schizo
- UNB
- Unband, The
- Unbelievable Truth
- Unbending Trees, The
- Unbending Trees, The Featuring Thorn, Tracey
- Unbound (dubstep)
- Unbowed
- Unbreakable (German Hard Rock group)
- Unbreakable Hatred (Death Metal band form Quebec)
- Unbroken
- Unbroken Expanse (Northern Territory, Australia rock band)
- Unbunny
- Unburier (UK Death Metal Band)
- Unbuttoned
- uncalc
- Uncanny (Swedish death metal)
- Uncanny Alliance
- Uncanny X-Men
- UNCHAIN (Japanese rock band)
- Unchained (UK Punk)
- Uncharted Shores (California band, formerly known as One Direction)
- Uncharted, The
- Unchosen Ones
- Unción Tropical (Christian music band)
- Uncle Acid & The Deadbeats
- Uncle Bard & The Dirty Bastards
- Uncle Bard and The Dirty Bastards
- Uncle Black (UK band Les King / Mike Aldridge / Paul Ashworth)
- Uncle Bonsai
- Uncle Brian
- Uncle Charlie
- Uncle Chris
- Uncle Deadly (The solo project of Kaizers Orcestra's Geir Zahl.)
- Uncle Devil Show, The
- Uncle Earl
- Uncle Ezra Ray
- Uncle Green
- Uncle Ho
- Uncle Jed
- Uncle Jumbo
- Uncle Kracker
- Uncle Kracker feat. Gray, Dobie
- Uncle Kracker feat. Kid Rock & Paradime
- Uncle Kracker feat. Lee, Jesse
- Uncle Lucius
- Uncle Luke
- Uncle Mega (French rapper)
- Uncle Moishy
- Uncle Murda
- Uncle Murda feat. Jadakiss, Benny the Butcher & Que Banz
- Uncle Murda feat. Que Banz
- Uncle Outrage
- Uncle Sam (dubstep artist, key track "Round the World Girls")
- Uncle Sam (US R&B singer, key track "I Don't Ever Want To See You Again")
- Uncle Sinner
- Uncle Slam
- Uncle Tupelo
- Uncle Vic
- Uncle Waffles
- Uncle Weevil (Swedish prog group)
- Unclubbed
- Unclubbed feat. Durrant, Zoe
- Unclubbed with Bailey, Abigail
- Unclubbed with Cavendish, Bess
- Uncluded, The (Aesop Rock & Kimya Dawson)
- Unco (Venezuela rock band)
- Uncommon Nasa (US rapper Paul Loverro, a.k.a. Nasa)
- Uncommonmenfrommars
- Unconditional
- uncoolclub
- Uncured
- Uncut (Canadian indie rock band)
- Und Bodevan
- Und wieder Oktober (Melancholic pop group from Cologne, Germany)
- Unda Surveillance
- Undacava
