- Unthank, Rachel & the Winterset
- Unthanks, The
- Until Death Overtakes Me
- Until December
- Until Further Notice
- Until I Wake
- Until June
- Until Rain
- Until the End (American metalcore band)
- Until the Ribbon Breaks
- Until the Ribbon Breaks & Run the Jewels
- Until We Are Ghosts
- Untiljapan
- untitled (halo)
- Untitled Band Project, The
- Untitled Project of Maks SF
- Unto Ashes
- Unto Others (heavy metal band from Portland, Oregon)
- Untold (UK electronic producer)
- Untoten
- Untouchable (Korean Hip-Hop Group)
- Untouchable 3
- Untouchables, The (Austrian Rhythm & Blues)
- Untouchables, The (mid 80s US ska/mod revival band)
- Untung Sonjaya
- Unturned
- Unusual Demont
- Unusual Suspects (UK hip hop)
- Unveil
- Unverkalt
- Unviar
- UNVS
- Unwanted, The (Irish Band)
- Unwed Sailor
- Unwell
- UNWELL (Rock/pop-punk band)
- Unwind, DJ (American Producer & Remixer)
- Unwinding Hours, The (Scottish alternative rock band)
- Unwoman
- Unword
- Unwound (US post-hardcore band)
- Unwrapped (hip‐hop songs covered in jazz style)
- Unwritten Law (1990- current American rock band)
- Unwritten Pages
- Unya (Finnish band)
- Unyielding Love (Grindcore/experimental band from Belfast, Northern Ireland)
- Unzane
- Unzucht
- Uochi Toki (Italian hip-hop band)
- Uomini in frac
- Up & Down
- uP & pG
- Up Close
- Up dharma Down
- Up Dharma Down
- Up From Here
- Up Front
- Up Hygh
- Up Up Down Down Left Right Left Right B A Start
- Up Up Girls (Kari)
- Up With People
- Up, Ari
- Up, Bustle & Out
- UP! (Hungarian band)
- UP10TION
- UPA Dance
- Upa!
- Upadhyay, Purushottam
- UPAFTER, The
- Upbeats, The (New Zealand drum n bass duo)
- Upbeats, The (50s US group)
- Upbeats, The feat. Baxter, Tasha
- Upbeats, The feat. Joe Dukie
- Upbeats, The feat. Mara TK
- Upbeats, The feat. Worboys, Ned
- Upchuck (Atlanta punk)
- Upchurch (country rapper)
- Upchurch feat. Mama Church
- Upchurch feat. Merkules & Jelly Roll
- Upchurch, Phil
- Upchurch, Phil, Combo
- updog
- Upercent (house)
- Upfront
- Upfux, The (New Jersey Ska band)
- Upgrade (NY hip-hop)
- Upgrade (Psychedelic trance duo from Israel [Raz Kfir & Udi Pilo])
- Uphill Battle
- Upiór
- Upjohn, Jed
