- Iqbal, Nabihah
- Ir Sais (Dutch-Carribean artist Irgwin Placido Sluis, stage name also stylized as Ir-Sais)
- IRA (Polish band)
- Ira (Mexican Power Metal Band)
- IRA (Feminism Rap from Madrid)
- Ira de Dios, La
- Ira Ironstrings
- Ira! (Brazilian rock band)
- Ira! feat. Pitty
- Ira! feat. Rosa, Samuel
- Iracundos, Los
- Iradier, Sebastián
- Írafár (Icelandic)
- IRAH (Adi Zukanović (keyboards) and Stine Grøn (vocals))
- Iraheta, Allison
- Iraka (french rapper / slammer)
- Irakere
- Irakere, Valdés, Chucho
- Irama (Italian singer and songwriter Filippo Maria Fanti)
- Irama feat. Epoque
- Irama feat. Guè
- Irama feat. Lazza
- Irama feat. Mr. Rain
- Irama feat. Rkomi
- Irama feat. Sfera Ebbasta
- Irama feat. Shablo
- Irama feat. Vegas Jones & Kolors, The
- Irama ft. William, Willy
- Iras (African rapper)
- Iration
- Iration feat. Slightly Stoopid
- Iratus (Vaggelis Gotovos)
- Iratxo
- Irawan, Ria
- Irdorath (Austria / Black Metal)
- Ireland, John (English composer)
- Ireland, John (South African pop)
- Ireland, Jordie
- Ireland, Mike and Holler
- İrem (Turkish pop)
- İrem, İlhan
- Irena (Polish band)
- Irencros
- Irene (Swedish band)
- Irene (aka Irene Stelmakovich)
- Irenegarry (Spanish singer-songwriter)
- Irepelusa
- Iress
- Irfan, Mohammed
- Irgens, Henrik (Danish multi-instrumentalist)
- Irglová, Markéta
- Irglová, Markéta and Hansard, Glen
- iri (Female vocalist/rapper)
- Iridium (Louisiana Rock Band)
- Iridium (Metal-Core band from Colorado, USA)
- Irie FM (Reggae band from Belgrade)
- Irie Love
- Irie Maffia
- Irie Maffia feat. Beenie Man
- Irie Révoltés
- Irie Souljah
- Irie, Evie (Australian Pop Singer)
- Irie, Jun (composer and arranger)
- Irie, The (Reggae/Alt Band from Arizona)
- Irie, Tippa
- Iriepathie
- Iriepathie feat. Irie Révoltés
- Iriepathie feat. Zos & Kaa, Uwe
- Irigy Hónaljmirigy
- Irina (Finnish singer Irina Saari)
- Irino, Miyu
- Iriondo, Silvia (Argentine ethnomusicologist, composer and singer)
- Iris (Texan synthpop band)
- IRIS (Romanian rock band)
- Iris (A pop / rock british group)
- Iris (Belgian Singer Laura van den Bruel)
- iRis (Idol group)
- IRIS (Portuguese Rock band)
- Iris (Australia)
- iris (Norwegian singer-songwriter)
- Iris (Montreal-based pop singer/drummer)
- Iris (shoegaze band from Toronto, Canada)
- Iris (Swedish psychedelic/progressive rock group)
- Iris & Rose: "Wild & Thorny"
- iris & SKAAR
- Iris Bevy
- Iris Doe (Project from Jeffrey Cain of The Church)
- Iris, Donnie
- Irisa
- Irish All-Stars