- Xochimilcas, Los
- XODIAC (South Korean boy group)
- xojira
- Xolo (L.A.-based dream pop duo)
- Xolotl (USA, Black Metal)
- XOMG POP!
- Xomu
- XONOR
- xooos
- XOR (US electronic musician from Asheville, NC)
- Xorcist
- Xordia
- Xori
- Xose Lois Romero & Aliboria
- xotox
- XOV (Swedish singer-songwriter)
- XOXO's, The
- Xoxocapa, Trío
- XP Voodoo
- XP-30
- XP8
- Xpansions (known for ‘Move Your Body’)
- Xpansions 95 (AKA Xpansions)
- XPDC
- Xperience (US rapper, a.k.a. XP)
- Xperiment (aggrotech band from Spain)
- Xploding Plastix
- Xploding Plastix feat. Cracknell, Sarah
- Xplore Yesterday
- Xplosn (edm artist)
- XPQ-21
- xPropaganda (Claudia Brücken und Susanne Freytag, former 'Propaganda')
- Xquizit, DJ
- Xquizit, DJ feat. Hilberts, Tim
- XRaidX
- Xramovi, Misha
- XRay5, The (LA post-punk band)
- XReal
- xRepresentx (American straight edge hardcore band)
- Xriz
- XRP Bags
- XS Project
- XS Project & Life of Boris
- XSakara
- XSARA
- Xscape
- xServitudex
- XSI (Psytrance project from France)
- XSOLEIL (NIJISANJI EN VTuber group)
- Xstasia
- XT
- Xtatik
- XTC (English rock band)
- Xtha
- xthedoc
- xthedoc feat. Jordan Parat
- XTIE (Hong Kong Solo Artist)
- xtinto (Portuguese Rapper)
- XTM (Catalan dance music act;Brothers Xasqui and Toni Ten)
- XTM & Chucky, DJ
- XTM & DJ Chucky
- Xtortion Audio
- XTR Human
- Xtract (UK punk band from Sheffield)
- XtraGreen
- Xtreme (US bachata group)
- Xtreme feat. Adrienne Bailon
- Xtreme Kids
- Xtreme Kids (Christian music group)
- Xtreme Team (Italian crew)
- XTRMST
- Xtrullor
- Xtruppaw
- xTyrantx
- Xu Xu Fang
- Xu, Lumi
- Xu, Song
- Xu, Weizhou
- Xu, Yiyang
- Xuan Huang (Taiwan Male Artist)
- Xuân, Nghi
- XuanXuan (Taiwanese singer)
- Xuclà, Toni
- Xue, Joker
- xUhrwerk
- Xuitcasecity
- Xul (Canadian metal)
- Xul Zolar
- Xulfi (Zulfiqar Jabbar Khan (Pakistani Artist))
- XUM (South Korean girl group)
