- 2D (Indonesian pop group)
- 2DB (Simon "Bassline" Smith & Andy Wright)
- 2DCAT
- 2econd Class Citizen feat. Ceschi
- 2EYES (South Korean girl group)
- 2Faces (canadian hip hop)
- 2far2jump
- 2FeetBino
- 2fox
- 2fox feat. Nandi
- 2Frères (Quebec folk duo)
- 2Gether
- 2hollis
- 2Hooks (Composers/Producers for Film & TV)
- 2Hounds
- 2Hurt (Italian band)
- 2i, Lil
- 2K (aka The KLF)
- 2KBABY
- 2KBABY & Marshmello
- 2Kvėpavimas (Lithuanian dance‐pop artist)
- 2Kvėpavimas & Bäsello
- 2Kvėpavimas ft. Iglė
- 2LADE (German rapper)
- 2lane (Mozambican DJ)
- 2LATE
- 2manydjs
- 2Mex
- 2Minds (Israeli psytrance group, Shauli & Miki Ifrah)
- 2NB
- 2ND (US rock / metal)
- 2nd Best
- 2nd Chapter of Acts
- 2nd Exit (Lester Duval & Alfa Mist)
- 2nd Exit & Thomas‐Dyke, Kaya
- 2nd Face
- 2nd Gen
- 2nd Generation Wu
- 2nd Grade
- 2nd II None (Rap duo from Compton, Los Angeles)
- 2nd II None feat. AMG & Quik, DJ
- 2nd Moon
- 2nd Roof (italian hip hop producers)
- 2nd Shift
- 2nd South Carolina String Band
- 2NE1
- 2NU
- 2Pac (US rapper)
- 2Pac & Clinton, George
- 2Pac & Danny Boy
- 2Pac & Half Deezy
- 2Pac & Nas
- 2Pac & Nate Dogg
- 2Pac & Notorious B.I.G., The
- 2Pac & Nutt‐So
- 2Pac & Outlawz
- 2Pac & Rich, Richie
- 2Pac & Snoop Dogg
- 2Pac & Snoop Dogg
- 2Pac & Stretch
- 2Pac + Outlawz
- 2Pac and Snoop Dogg
- 2Pac feat. 50 Cent
- 2Pac feat. A3 & Jay Rock
- 2Pac feat. Above the Law
- 2Pac feat. Big Syke
- 2Pac feat. Big Syke
- 2Pac feat. Big Syke, E.D.I. Mean of the Outlawz
- 2Pac feat. Boot Camp Clik
- 2Pac feat. Buckshot & Cocoa Brovaz
- 2Pac feat. C-Bo
- 2Pac feat. Candy Hill
- 2Pac feat. Clinton, George
- 2Pac feat. Cole, Keyshia
- 2Pac feat. Danny Boy
- 2Pac feat. Danny Boy, Big Syke & CPO Boss Hogg
- 2Pac feat. Danny Boy, Big Syke & CPO Boss Hogg
- 2Pac feat. Danny Boy, Big Syke & CPO Boss Hogg
- 2Pac feat. Digital Underground
- 2Pac feat. Dillinger, Daz, Kurupt, Redman & Method Man
- 2Pac feat. DMX & Xzibit
- 2Pac feat. Dogg Pound, Tha
- 2Pac feat. Dre, Dr.
- 2Pac feat. Dre, Dr. & Troutman, Roger
- 2Pac feat. Dwele
- 2Pac feat. E‐40, B‐Legit, C-Bo & Rich, Richie
- 2Pac feat. E‐40, B‐Legit, C‐Bo & Rich, Richie
- 2Pac feat. E.D.I. Mean & Brown, Sleepy
- 2Pac feat. E.D.I. Mean & Kastro
- 2Pac feat. Fatal, Hussein